What types of human activity have led to the thinning of the ozone? What human health conditions are related to this phenomenon?

The significant thinning of Earth's protective layer was first detected in the 1970s, and scientists found that the anomaly was caused by the manufacture of chlorofluorocarbons (CFCs), which are used in refrigerators and aerosol sprays. In the late 1970s, the famed ozone hole above Antarctica was discovered. Another reason could be that newer man-made pollutants are eroding the ozone layer. The gasses in question include "extremely short-lived chemicals," such as dichloromethane, which is employed in numerous industrial processes. The "good ozone" found high in the atmosphere is in contrast to the "bad ozone" found near the surface, which is pollution and can cause respiratory issues. In a way, humanity has turned the protective layer that is supposed to be a shield into a sword with a blade instead of a handle.